specified its important role as being a regulator of innate and acquired immunity, pharmacological or immunological modulation of MIF exercise could possibly provide new procedure alternatives to the administration of acute and chronic inflammatory conditions.
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As a pro-inflammatory mediator, MIF has become shown to be implicated in the pathogenesis of intense sepsis and septic shock, acute respiratory distress syndrome, and several other inflammatory and autoimmune health conditions, including rheumatoid arthritis, glomerulonephritis and inflammatory bowel disorders.
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The mitochondrial membrane prospective was evaluated using the fluorescent probe TMRM dye (Invitrogen) According to the manufacturer’s Directions.